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Tensilon makes symptoms worse; Tensilon works almost immediately to cause an increase in musclestrength by increasing the amount of acetylcholine at the myoneural junction.

When switching a patient to liothyronine sodium tablets, liothyronine sodium injection should be discontinued, and oral therapy should be initiated at a low dosage and increased gradually based on the patient's response.

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Rapid restoration of normal serum T 4 concentrations is essential for preventing the adverse effects of congenital hypothyroidism on intellectual development as well as on overall physical growth and maturation.

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However, our data do not allow us to exclude absolutely an association between thyroid dysfunction and MD, as only one patient suffered from hypothyroidism when the study was performed and no data were available on the thyroid status of MD patients at the beginning of L-T 4 therapy.

Only one patient in the control group developed subclinical hypothyroidism during the same time period.

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Such antithyroid drugs "usually do not cure the patient" and have "rare but potentially life-threatening" adverse effects including inhibition of bone marrow function (agranulocytosis, granulocytopenia, aplastic anemia, thrombocytopenia), drug fever, a lupus-like syndrome, insulin autoimmune syndrome (can result in hypoglycemia, coma), hepatitis, inflammation of arteries, decreased level of prothrombin (for blood clotting), and more.

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